Thursday, October 21, 2010

GIST

Most Common site-Stomach
Origin-C Kit Receptor of Tyrosin Kinase
C/f- Asymptomatic and incidental finding
-obstruction
-perforation
-bleeding
inv- EUS AND GUIDED biopsy
t/t- D1 gasterectomy
Adjuvent t/t- Imatinib

Thursday, October 14, 2010

Risk factor for breast cancer

Germline mutation-BRCA 1
Personal history of breast cancer
Radiation exposure
Family history -first degree family in premenopausal
Age at first child birth-older than 30yr
Hormonal replacement thrapy
Early menarche -Younger than 12yr
late menopause-older than 55yr

Role of Sentinel lymph node biopsy in gyne ca

Only in Valval malignency

Saturday, October 2, 2010